AIDS has created considerable concern among the public regarding being
transfused with potentially infectious blood. However, autologous blo
od donations are still not maximally provided nor utilized. Significan
t heart disease disqualifies all allogeneic and most autologous blood
donors (American Association of Blood Banks (AABB) Standards 1994). Di
squalification is based on the widespread belief that donating blood c
ould possibly be detrimental to their health. However, this belief has
not been sufficiently documented. Sixty-eight donors (ages 14-84 year
s), all with histories of significant cardiac diseases, donated 111 un
its of whole blood (13 units). Twenty-eight patients donated 1 unit, 3
7 donated 2 units, and three patients donated 3 units. Fifty-nine pati
ents had ischemic heart disease, and nine had valvular heart disease (
five with mitral stenosis and four with mitral valve prolapse). No pat
ient received erythropoietin, and only one received equal volume repla
cement with normal saline during donation. All these patients eagerly
wished to donate in spite of being informed of the possible complicati
ons. No patient wishing to donate has been refused, and none has exper
ienced any adverse consequences from donating. Forty-four patients und
erwent total hip/knee replacements. Only 56 units (50%) were transfuse
d to 37 patients (54%). Although our experience is limited, it appears
that many patients with histories of well established cardiac disease
s can easily tolerate donating blood without compromising their health
. (C) 1997 Elsevier Science Ltd.