LEWIS-ACID ASSISTED REACTIONS OF N-(ALPHA-AMINOALKYL)BENZOTRIAZOLES AND UNACTIVATED ALKENES FOR THE FACILE SYNTHESIS OF 4-SUBSTITUTED, 2,4-SUBSTITUTED, AND 3,4-SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINES
Ar. Katritzky et al., LEWIS-ACID ASSISTED REACTIONS OF N-(ALPHA-AMINOALKYL)BENZOTRIAZOLES AND UNACTIVATED ALKENES FOR THE FACILE SYNTHESIS OF 4-SUBSTITUTED, 2,4-SUBSTITUTED, AND 3,4-SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINES, Journal of heterocyclic chemistry, 34(4), 1997, pp. 1259-1262
A range of substituted tetrahydroquinolines have been synthesized from
benzotriazole derivatives and unactivated alkenes in the presence of
a Lewis acid. These reactions utilize readily available starting mater
ials and mild reaction conditions, and give high yields. The reaction
mechanisms are discussed.