Descending necrotizing mediastinitis (DNM) is a lethal process origina
ting from odontogenic, pharyngeal, or cervical infectious sources that
descends along fascial planes into the mediastinum. Despite earlier u
se of antibiotics and surgical drainage, the mortality (>50%) has chan
ged little since the first large series reported in the preantibiotic
era. The surgical management remains controversial, with support rangi
ng from cervical drainage alone to cervical drainage and routine thora
cotomy. We report a case of thoracoscopic drainage and debridement of
a mediastinal abscess resulting from descending necrotizing mediastini
tis. The decreased morbidity of this approach compared with posterolat
eral thoracotomy and the improved drainage of the mediastinum compared
with cervical drainage support this method as an attractive managemen
t of patients with DNM.