J. Kjellstrom et Skc. Elmroth, LARGE VARIATION OF RATES FOR PLATINATION OF PHOSPHOROTHIOATE-CONTAINING OLIGONUCLEOTIDES - END EFFECTS AND COUNTER ION INFLUENCE, Chemical communications, (18), 1997, pp. 1701-1702
The rate of site-specific platination of short oligonucleotides can be
varied up to 500 times by a change of the bulk composition and the mo
lecular environment surrounding the binding site.