THE FREQUENCY OF ANTISPERM ANTIBODIES IN THE CERVICAL-MUCUS OF WOMEN WITH POOR POSTCOITAL TESTS AND THEIR EFFECT ON PREGNANCY RATES

PROBLEM: To determine the impact of the presence of antisperm antibodi es (ASAs) in the cervical mucus of female partners in couples with une xplained poor postcoital tests (PCT). Furthermore, the efficacy of int rauterine insemination (IUI) in these same patients was determined by pregnancy rates (PRs). METHOD: Pregnancy rates following IUI in patien ts with infertility and poor postcoital tests, whether the cervical mu cus was positive or negative for ASAs, were evaluated. RESULTS: The 6- month PRs were similar in the ASA negative (40.5%) versus the positive (42.4%) group. CONCLUSIONS: It appears that the antifertility effect of ASA may be mainly the immobilization of sperm in the cervical mucus , and thus, performing IUI may effectively correct the problem.