ADSORPTION AND DESORPTION OF CEPHALOSPORIN-C ON NONIONIC POLYMERIC SORBENTS

Adsorption and desorption of cephalosporin C on nonionic polymeric sor bents were studied in order to obtain basic information on recovering cephalosporin C from aqueous solutions. The sorbents were polystyrene- based macroreticular resins with different sorptive capacity and pore- size distribution. Cephalosporin C adsorbed on these sorbents was then desorbed by aqueous isopropyl alcohol (IPA) solutions. Adsorption equ ilibrium data of cephalosporin C and IPA on these sorbents were found to fit the Freundlich equation and the desorption of cephalosporin C b y IPA was described by a competitive adsorption model based on the ide al adsorbed solution theory. Furthermore, a simple dynamic model was f ormulated to describe both adsorption and desorption breakthrough curv es of cephalosporin C. (C) 1997 Elsevier Science B.V.