IN-VITRO BACTERICIDAL ACTIVITY OF 7 ANTIB IOTICS AND 4 COMBINATIONS AGAINST N-MENINGITIDIS

Citation
Jy. Nizou et al., IN-VITRO BACTERICIDAL ACTIVITY OF 7 ANTIB IOTICS AND 4 COMBINATIONS AGAINST N-MENINGITIDIS, Pathologie et biologie, 42(5), 1994, pp. 393-398
Citations number
12
Categorie Soggetti
Pathology
Journal title
ISSN journal
03698114
Volume
42
Issue
5
Year of publication
1994
Pages
393 - 398
Database
ISI
SICI code
0369-8114(1994)42:5<393:IBAO7A>2.0.ZU;2-G
Abstract
The authors studied, with a time-kill curve method, in a derived Hafiz medium broth the bactericidal effect of 7 antibiotics and 4 asssociat ions against N. meningitidis. Their results show a better bactericidal effect for penicillin G, ampicillin and chloramphenicol. Pefloxacin a nd ceftriaxon are less efficient. The association ampicillin + chloram phenicol in vitro shows no antagonism and has a good bactericidal acti vity at the early stages of bactericidal killing with N. meningitidis.