Jy. Nizou et al., IN-VITRO BACTERICIDAL ACTIVITY OF 7 ANTIB IOTICS AND 4 COMBINATIONS AGAINST N-MENINGITIDIS, Pathologie et biologie, 42(5), 1994, pp. 393-398
The authors studied, with a time-kill curve method, in a derived Hafiz
medium broth the bactericidal effect of 7 antibiotics and 4 asssociat
ions against N. meningitidis. Their results show a better bactericidal
effect for penicillin G, ampicillin and chloramphenicol. Pefloxacin a
nd ceftriaxon are less efficient. The association ampicillin + chloram
phenicol in vitro shows no antagonism and has a good bactericidal acti
vity at the early stages of bactericidal killing with N. meningitidis.