EFFECT OF CAFETERIA DIET ON ALPHA-MG INTESTINAL-ABSORPTION IN RATS

The effect of a cafeteria diet (a hypercaloric diet) on the accumulati ve ability of the mediated and non-mediated small intestine transport of alpha-methyl-D-glucoside (alpha-MG) in developing female Wistar rat s was studied using everted intestinal slices. Cafeteria diet increase d intestinal active transport and decreased intestinal passive diffusi on of alpha-MG in 30-day-old rats. No differences in alpha-MG intestin al absorption were found in cafeteria vs control rats after the develo pment of obesity in cafeteria diet fed rats. A link between gastrointe stinal functions and the development of obesity induced by cafeteria d iet is suggested.