SERODIAGNOSIS OF CELIAC-DISEASE

The detection rate of celiac disease greatly underestimates its preval ence. This is the result of lack of awareness of the many manifestatio ns of the condition and the requirement for at least one small intesti nal biopsy for diagnosis. The advent of effective serologic tests for the condition heralds a new era of non-invasive testing. The clinical utility and acceptance of these tests is limited by a lack of standard ization of both the techniques used and variability of reference range s quoted.