Purpose. We evaluated the reliability of prenatal sonography and the u
sefulness of the umbilical vein and artery diameter ratio, transverse
umbilical artery diameter, and systolic-diastolic ratio in detecting s
ingle umbilical artery (SUA). Methods. In 24 of 6,970 fetuses, SUA was
detected using prenatal sonography and confirmed at birth. These case
s were retrospectively reviewed. Results. Four fetuses had major malfo
rmations, and 1 had a minor anomaly. Thirteen fetuses with SUA underwe
nt chromosomal analysis, and only 2 had abnormal karyotypes. Most of t
he SUA fetuses had a normal systolic-diastolic ratio. Conclusions. Our
retrospective study determined that the prognosis of SUA fetuses is g
ood when there is no concurrent anatomic or chromosomal abnormality. A
lthough some reports claim that the transverse umbilical artery diamet
er or the ratio between umbilical vein and artery diameters can predic
t SUA, we found no significant improvement in the recognition of SUA u
sing these parameters. (C) 1997 John Wiley & Sons, inc.