THE ELEMENTS OF RELIABILITY THEORY IN THE MATHEMATIC ANALYSIS OF HALF-LIFETIMES OF ENZYMATIC PROTEINS

Citation
Gv. Kudryavtseva et al., THE ELEMENTS OF RELIABILITY THEORY IN THE MATHEMATIC ANALYSIS OF HALF-LIFETIMES OF ENZYMATIC PROTEINS, Biofizika, 42(4), 1997, pp. 840-843
Citations number
6
Categorie Soggetti
Biophysics
Journal title
ISSN journal
00063029
Volume
42
Issue
4
Year of publication
1997
Pages
840 - 843
Database
ISI
SICI code
0006-3029(1997)42:4<840:TEORTI>2.0.ZU;2-1
Abstract
A definition of a new molecular-biological category - ''enzymic functi onal system'' is given. The mechanisms of reliability of its functioni ng in vivo were analyzed. The half-lifetime, decay rate constants and the rate of synthesis for a number of enzymic proteins were quantified . The vector of functional activity of the enzymic system is composed of three constituents: a static quantity t(1/2), half-lifetime and two dynamic quantities, K-s and K-d, the rate constants of synthesis and decay. It is K-s and K-d determine the reliability profile of the enzy mic functional system and its quality.