PROBLEMS IN THE MEASUREMENT OF 8-OXOGUANINE IN HUMAN DNA - REPORT OF A WORKSHOP, DNA OXIDATION, HELD IN ABERDEEN, UK, 19-21 JANUARY, 1997

Oxidative DNA damage is widely believed to play a role in cancer aetio logy, It is therefore important to be able to assess it, both as an in dex of cancer risk, and in experiments to test agents with a potential to reduce oxidative damage, such as dietary antioxidants, However, th ere is an alarming discordance in estimates of concentrations of oxida tive damage in human DNA, largely attributable to the kind of method u sed to measure it, A meeting was held recently at the Rowett Research Institute in Aberdeen to address this problem.