OBJECTIVE: To identify factors involved in the development of fetal ce
phalohematoma from vacuum extraction. STUDY DESIGN: Patients at greate
r than or equal to 34 weeks' gestation were randomly assigned to deliv
ery by vacuum (n=322) using the continuous (n= 164) or intermittent (n
= 158) technique. Neonatal outcome with cephalohematoma was analyzed s
ubse quently and related to prospectively recorded data. RESULTS: Appr
oximately equal numbers of cephalohematoma were recorded in the two gr
oups (continuous 20, intermittent 17; P =.686). Station at point of ap
plication (P=.008), increasing asynclitism (P <.001) and increasing ap
plication to delivery time (P=.002) correlated significantly with ceph
alohematoma. Only the last two factors achieved significance after ste
pwise multiple logistic regression analysis. Factors that did not achi
eve statistical significance were gestational age (P=.755), birth weig
ht (P =.982), instrumental rotation (P =.896) and previous vaginal del
ivery (P=.051). CONCLUSION: In this prospective, randomized, controlle
d trial of vacuum-assisted delivery, the only predelivery factor found
to predispose to neonatal cephalohematoma formation was increasing as
ynclitism. Although cephalohematoma formation was move likely to devel
op as the duration of vacuum application increased during delivery, on
ly 28% of neonates exhibited this finding when the time from vacuum ap
plication to delivery exceeded five minutes.