M. Basbug et al., RECURRENT MOLAR PREGNANCY AFTER OVULATION INDUCTION AND REPEAT OVULATION INDUCTION - A CASE-REPORT, Journal of reproductive medicine, 42(9), 1997, pp. 600-602
BACKGROUND: Although hydatidiform mole is not commonly encountered fol
lowing ovulation induction, patients who have already had molar pregna
ncies are at increased risk of developing further molar diseases with
worsening histologic characteristics. That fact underlies the ethical
dilemma of repeat ovulation induction. CASE: A 38-year-old woman, grav
ida 3, para 0, had three consecutive episodes of hydatidiform subseque
nt to clomiphene citrate and gonadotropin ovulation induction. She see
ms to be the first in the literature to develop three consecutive mola
r pregnancies without a normal intrauterine pregnancy. CONCLUSION: Alt
hough ovulation induction commenced again in this patient after she ga
ve informed consent, the risks underlying the ethical dilemma persist.