Psychotropic drugs are frequently used in both psychiatric and general
medical practice. Familiarity with common side effects and their mana
gement may assist psychiatrists in the selection of agents to suit ind
ividual patient needs, The authors describe the morphologic features a
nd pathologic basis of cutaneous reactions to drugs and discuss the co
mmon and reported cutaneous side effects of psychotropic drugs, Althou
gh most dermatologic reactions to drugs follow a benign course after d
rug discontinuation, more serious effects are known to occur with cert
ain agents. An overview of the diagnosis and management of these adver
se drug reactions is provided.