E. Zrenner et al., THE DEVELOPMENT OF SUBRETINAL MICROPHOTODIODES FOR REPLACEMENT OF DEGENERATED PHOTORECEPTORS, Ophthalmic research, 29(5), 1997, pp. 269-280
There are presently several concepts to restore vision in blind or hig
hly visually handicapped persons by implanting electronic devices into
the eye in order to partially restore vision, Here, the approach to r
eplace retinal photoreceptors by a subretinally implanted microphotodi
ode array (MPDA) is summarized, A survey is given on the present state
of the development of MPDAs, the possibility of in vitro and in vivo
tests as well as first results on biocompatibility and histology. Addi
tionally, electrophysiological recordings in rabbits and rats are pres
ented which have received such subretinal implants.