THE DEVELOPMENT OF SUBRETINAL MICROPHOTODIODES FOR REPLACEMENT OF DEGENERATED PHOTORECEPTORS

Citation
E. Zrenner et al., THE DEVELOPMENT OF SUBRETINAL MICROPHOTODIODES FOR REPLACEMENT OF DEGENERATED PHOTORECEPTORS, Ophthalmic research, 29(5), 1997, pp. 269-280
Citations number
8
Categorie Soggetti
Ophthalmology
Journal title
ISSN journal
00303747
Volume
29
Issue
5
Year of publication
1997
Pages
269 - 280
Database
ISI
SICI code
0030-3747(1997)29:5<269:TDOSMF>2.0.ZU;2-A
Abstract
There are presently several concepts to restore vision in blind or hig hly visually handicapped persons by implanting electronic devices into the eye in order to partially restore vision, Here, the approach to r eplace retinal photoreceptors by a subretinally implanted microphotodi ode array (MPDA) is summarized, A survey is given on the present state of the development of MPDAs, the possibility of in vitro and in vivo tests as well as first results on biocompatibility and histology. Addi tionally, electrophysiological recordings in rabbits and rats are pres ented which have received such subretinal implants.