CHEMICAL MODIFICATION OF GLYCOSAMINOGLYCANS SELECTIVE 2-SULFATION OF D-GLUCURONIC ACID UNITS IN HEPARAN-SULFATE

Authors
KOVENSKY J CIRELLI AF
Citation
J. Kovensky et Af. Cirelli, CHEMICAL MODIFICATION OF GLYCOSAMINOGLYCANS SELECTIVE 2-SULFATION OF D-GLUCURONIC ACID UNITS IN HEPARAN-SULFATE, Carbohydrate research, 303(1), 1997, pp. 119-122
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
303
Issue
1
Year of publication
1997
Pages
119 - 122
Database
ISI
SICI code
0008-6215(1997)303:1<119:CMOGS2>2.0.ZU;2-3
Abstract
O-Sulfation of heparan sulfate was performed in conditions that minimi se N-desulfation. NMR spectra and methylation analysis of sulfated hep aran sulfate confirmed the selective substitution at O-2 of glucuronic acid units. (C) 1997 Elsevier Science Ltd.