APLASTIC-ANEMIA IN RURAL THAILAND - ITS ASSOCIATION WITH GRAIN FARMING AND AGRICULTURAL PESTICIDE EXPOSURE

Authors
ISSARAGRISIL S CHANSUNG K KAUFMAN DW SIRIJIRACHAI J THAMPRASIT T YOUNG NS ANDERSON T LEAVERTON PE PIANKIJAGUM A PORAPAKKHAM Y SHAPIRO S VANNASAENG S SOMPRADEEKUL S VUTHIVATANAKUL T SRIRATANASATAVORN C YAMCHAROEN C LAEWSIRI P KITTIMONGCOLPORN S TEPMONGCOL K WONGKONGDEJ R VEJJAPINAND R KIATVIRAKUL V KARENG K SUVATTE V INTARAGUMTHORNCHAI T CHANCHARUNEE S PRAYOONWIWAT V SEKSAN P CHUANSUMRIT A CHINARAT V ANGKURAVORAKUL S ATICHARTKARN V CHUTIPONG S FUCHAROEN S HATHIRAT P ISARANKURA P JETSRISUPARB A JOOTAR S KIATKACHORNTADA N KITKORNPAN S LAOHAVINIJ S LAOSOMBAT V LEKHAKUL A MAHASANDANA C MAKORNKAEWKAYOON V NITIYANONT P POOTRAKUL P SINGHAPAN K SIRITANARATANAKUL N SONAKUL D SRICHAIKUL T SRIPAISAL T SUCHARITCHAN P SUKPANICHNAND S SUKPANICHNAND SY SUPRADIT P SUWANWELA N TANPHAICHITR VS TANTECHANURAK C TANYAVUDH K VATANAVICHARN S VISUDHIPHAN S WANACHIWANAWIN W WATANANUKUL P
Citation
S. Issaragrisil et al., APLASTIC-ANEMIA IN RURAL THAILAND - ITS ASSOCIATION WITH GRAIN FARMING AND AGRICULTURAL PESTICIDE EXPOSURE, American journal of public health, 87(9), 1997, pp. 1551-1554
Citations number
9
Categorie Soggetti
Public, Environmental & Occupation Heath","Public, Environmental & Occupation Heath
Journal title
American journal of public health → ACNP
ISSN journal
00900036
Volume
87
Issue
9
Year of publication
1997
Pages
1551 - 1554
Database
ISI
SICI code
0090-0036(1997)87:9<1551:AIRT-I>2.0.ZU;2-S
Abstract
Objectives. A population-based cage-control study was conducted to elu cidate the incidence and etiology of aplastic anemia in Thailand. Meth ods. Case patients and hospital control patients:were enrolled in thre e regions from 1989 to 1994; data were collected by interview. Results . Forty-six percent of 81 case patients and 19% of 295 control patient s from Khonkaen were grain farmers (estimated relative risk [RR] = 2.7 , 95% confidence interval [CI] = 1.4, 5.2). Sixteen percent of case pa tients and 6% of control patients used agricultural pesticides (estima ted RR = 2.7, 95% CI = 1.1, 6.6). The association with grain farming r emained among those not exposed to pesticides. In Songkla, 16% of 43 c ase patients and 2% of 181 control patients were grain farmers (crude RR estimate = 11, 95% CI = 3.4, 35). Conclusions. The relation. of apl astic anemia to grain farming may partly explain the high incidence of aplastic anemia in Thailand.