We present the first results from a recent survey of molecular lines i
n L1157, a highly collimated bipolar molecular outflow driven by a cla
ss 0 protostar. These observations are used to study the chemical alte
rations produced by a violent, highly collimated outflow. Different mo
lecular lines are observed to trace different components of the gas. S
ome molecules (C3H2, N2H+, (HCO+)-C-13, DCO+) are abundant in the quie
scent medium but are not observed at high velocities. Lines from these
molecules are the best tracers of the concentration of dense gas arou
nd the protostar. In addition, we find that some otherwise rare molecu
les (e.g., SiO, CH3OH, H2CO, HCN, CN, SO, and SO2) are enhanced by at
least an order of magnitude at the shocked region. Our observations pr
ovide estimates of the enhancement factors for such species. Strong gr
adients in the chemical composition are observed along the outflow blu
e lobe, which could be due to the evolution in time of the chemical pr
ocesses. We briefly discuss the chemistry of the most important molecu
les, devoting special attention to the species that are thought to be
abundant in interstellar ice mantles.