P. Prasittirat et al., EFFICACY OF BITHIONOL SULFOXIDE, NICLOSAMIDE AND FENBENDAZOLE AGAINSTNATURAL RUMEN FLUKE INFECTION IN CATTLE, Helminthologia, 34(3), 1997, pp. 155-157
Forty-eight cattle naturally infected with lumen flukes were used to a
ssess the efficacy of three anthelmintics against rumen flukes. The in
fected animals were divided into 4 groups: group 1 consisting of 18 an
imals, group 2 of 18 and group 3 of 6 were treated with bithionol sulf
oxide at a dose of 90 mg/kg, niclosamide at 90 mg/kg and fenbendazole
at 7.5 mg/kg, respectively. Group 4 composed of 6 cattle was the untre
ated positive control. Faecal samples were collected at one week inter
val for 9 weeks after drug administration. Faecal examination was perf
ormed by the beads technique for eggs output per gram (EPG). Efficacy
of each anthelmintic against lumen fluke infection was assessed by the
rate of egg reduction. The results showed that bithionol sulfoxide is
the most effective against natural lumen fluke infections.