Ci. Riegel et Jm. Slavicek, CHARACTERIZATION OF THE REPLICATION CYCLE OF THE LYMANTRIA-DISPAR NUCLEAR POLYHEDROSIS-VIRUS, Virus research, 51(1), 1997, pp. 9-17
The life cycle of the Lymantria dispar nuclear polyhedrosis virus (LdM
NPV) was characterized through analysis of budded virus (BV) release,
the temporal formation of polyhedra, the temporal transcription patter
n of representative early, late, and hyper-expressed late genes, and t
he onset of DNA replication in the Ld652Y cell line. Transcripts from
the LdMNPV immediate early gene G22 were detected 4 h post infection (
h p.i.). The late and hyper-expressed late p39 capsid and polyhedrin g
enes were initially transcribed at approximately 20 and 24 h p.i., res
pectively. Viral DNA replication initiated at approximately 18-20 h p.
i. Budded virus was released from infected cells between 24 and 36 h p
.i., and polyhedra were first detected at approximately 48 h p.i. (C)
1997 Elsevier Science B.V.