A VERSATILE ROUTE TO CONJUGATED HYDROXY (E,Z,E,E)-TETRAENOIC ACIDS - HIGHLY CHEMOSELECTIVE AND STEREOSELECTIVE SYNTHESIS OF LIPOXIN B-4

Authors
ALAMI M CROUSSE B LINSTRUMELLE G MAMBU L LARCHEVEQUE M
Citation
M. Alami et al., A VERSATILE ROUTE TO CONJUGATED HYDROXY (E,Z,E,E)-TETRAENOIC ACIDS - HIGHLY CHEMOSELECTIVE AND STEREOSELECTIVE SYNTHESIS OF LIPOXIN B-4, Tetrahedron : asymmetry, 8(17), 1997, pp. 2949-2958
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
17
Year of publication
1997
Pages
2949 - 2958
Database
ISI
SICI code
0957-4166(1997)8:17<2949:AVRTCH>2.0.ZU;2-I
Abstract
A highly convergent total stereocontrolled synthesis of lipoxin Bq is described by an efficient Pd-catalyzed coupling reaction of two easily accessible chiral synthons 2 and 3 without any protection-deprotectio n sequence of the alcohol functions. (C) 1997 Elsevier Science Ltd.