THE VALUE OF IMMUNOGLOBULIN AND COMPLEMENT LEVELS IN THE EARLY DIAGNOSIS OF NEONATAL SEPSIS

Serum IgG, IgG1, G2, G3, G4, IgM, C3c and C4 concentrations were measu red in 24 term neonates with sepsis and 17 healthy normal neonates of similar age, sex and weight (control group). The serum IgG, IgG1, G2, G3, G4, IgM, C3c, and C4 levels were similar in the patients with seps is and the control group (p > 0.05). In the neonates with sepsis, seru m IgG, G1, G2, IgM and C4 levels were not significantly different betw een the Ist and 10th days, while there were significant differences fo r IgG3, G4 and C3e (p < 0.05). We conclude that the serum levels of Ig G, IgG1, G2, G3, G4, IgM, C3e and C4 concentrations are of no value fo r the early diagnosis of neonatal sepsis.