DSM IV preserves the boundary between schizoaffective disorder and sch
izophrenia, yet validation of the former condition remains incomplete.
The prevalent view that schizoaffective disorder is a less serious co
ndition than schizophrenia suggests that cognitive disturbance might b
e less severe and possibly different from that found in schizophrenia.
We investigated a well-characterized cognitive difficulty in schizoph
renia, the relative lack of gain in verbal recall when context is incr
eased, in samples of patients and normal controls. Subjects with schiz
ophrenia (n=19) were individually matched for age, sex, and recall per
formance with patients diagnosed with schizoaffective disorder (n = 19
) and major depression (n = 19); and with normal controls (n=19). Pati
ents were also matched on duration of illness. The results indicate th
at schizophrenic subjects attain smaller gains in recall when context
is increased compared to depressed and normal controls, a finding cons
istent with previous results. Schizophrenic and schizoaffective subjec
ts, however, did not differ in recall gain on this task. We conclude t
hat schizoaffective subjects cannot be distinguished from schizophreni
c subjects on this cognitive feature. (C) 1997 Elsevier Science B.V.