THE EFFECT OF AN ANTIPHLOGISTIC INCORPORATED IN LIPOSOMES ON EXPERIMENTALLY-INDUCED INFLAMMATION

Authors
SCHRAMLOVA J BLAZEK K OTOVA B BARTACKOVA I HULINSKA D
Citation
J. Schramlova et al., THE EFFECT OF AN ANTIPHLOGISTIC INCORPORATED IN LIPOSOMES ON EXPERIMENTALLY-INDUCED INFLAMMATION, Folia biologica, 43(5), 1997, pp. 195-199
Citations number
6
Categorie Soggetti
Biology
Journal title
Folia biologica → ACNP
ISSN journal
00155500
Volume
43
Issue
5
Year of publication
1997
Pages
195 - 199
Database
ISI
SICI code
0015-5500(1997)43:5<195:TEOAAI>2.0.ZU;2-P
Abstract
The antiphlogistic Ibuprofen incorporated in liposomes caused a decrea se of the inflammatory edema induced by Carrageenan in the distal part of the rat's hind leg after both the intramuscular and percutaneous a dministration. The antiphlogistic effect of free Ibuprofen in the crea m was weaker. Intramuscular administration of empty liposomes slowed d own in the initial stages the development of inflammation and slightly diminished the size of edema.