SUSCEPTIBILITY OF 98 CLINICAL ISOLATES OF LEGIONELLA TO MACROLIDES AND QUINOLONES USING THE ETEST

Isolates of Legionella from 98 patients with Legionnaires disease hosp italized in Columbus, Ohio, LISA between 1991 through 1995 were tested for antimicrobial susceptibility to macrolides and quinolones using t he Etest. Most (87%) isolates were Legionella pneumophila serogroup 1. All isolates tested remain susceptible to erythromycin, azithromycin, clarithromycin, ciprofloxacin, ofloxacin, and levofloxacin. In vitro susceptibility testing of Legionella to representative macrolides and quinolones should be considered to detect the emergence of resistant i solates. (C) 1997 Elsevier Science Inc.