PEDIATRIC HEPATOBILIARY DISEASE

There have been improved insights into the diagnosis, pathophysiology, and treatment of pediatric hepatobiliary disorders. As the longevity of patients with cystic fibrosis has increased, hepatobiliary complica tions have become more significant. Newer diagnostic methods and treat ment modalities are discussed. Insights into the genetics, pathophysio logy, and treatment of progressive familial intrahepatic cholestasis ( Byler's syndrome) are presented. Parenteral nutrition-associated chole stasis continues to be a significant problem for the neonate. Potentia l causes and treatment modalities are discussed.