A. Nonomura et al., HEPATIC HILAR INFLAMMATORY PSEUDOTUMOR MIMICKING CHOLANGIOCARCINOMA WITH CHOLANGITIS AND PHLEBITIS - A VARIANT OF PRIMARY SCLEROSING CHOLANGITIS, Pathology research and practice, 193(7), 1997, pp. 519-525
Inflammatory pseudotomur (IPT) of the liver is rare. We present a case
of hepatic IPT mimicking cholangiocarcinoma in which the tumor was lo
cated at the left porta hepatis. The patient was a 64-year-old man in
whom abnormal liver function test results had been noted incidentally
during an annual health checkup in 1993: the patient declined to go to
the hospital for further examination. At the annual health checkup th
e following year, abnormal liver function test results were noticed ag
ain, and this time he did go to a hospital, where a hepatic mass was f
ound. Laboratory test results were unremarkable. Based on the location
of the lesion and the findings of a variety of imaging modalities, su
ch as ultrasound and computed tomography examination, the lesion was p
reoperatively diagnosed as hilar cholangiocarcinoma and was surgically
resected. Pathologic examination of the resected lesion, however, rev
ealed that it was not a true trumor but an inflammatory pseudotumor wi
th marked destructive and sclerosing cholangitis mimicking primary scl
erosing cholangitis (PSC) and obliterative phlebitis. Since the locati
on and features of the tumor in the present case are very pertinent to
the relationship between IPT and PSC, we describe its clinical and hi
stologic features and discuss the findings in relation to PSC in the c
ontext of our literature review.