ENANTIOMERIC SEPARATION OF CARBOXYLIC-ACIDS HAVING CHIRAL CENTERS REMOTE FROM THE CARBOXYL GROUP BY LABELING WITH A CHIRAL FLUORESCENT DERIVATIZATION REAGENT
K. Akasaka et al., ENANTIOMERIC SEPARATION OF CARBOXYLIC-ACIDS HAVING CHIRAL CENTERS REMOTE FROM THE CARBOXYL GROUP BY LABELING WITH A CHIRAL FLUORESCENT DERIVATIZATION REAGENT, Tetrahedron letters, 38(39), 1997, pp. 6853-6856
Enantiomeric separations of 2-, 3-, 4-, 5- and 6-methyl fatty acids an
d 3-, 4- and 5-hydroxy fatty acids derivatized with (S)-(+)-2-(anthrac
ene-2,3-dicarboximido)-1-propyl trifluoromethanesulfonate are describe
d. Although there are 4-8 bond distances between the chiral centers of
these diastereomeric derivatives, they are separated on HPLC and dete
cted at fmol levels. (C) 1997 Elsevier Science Ltd.