NOVEL SYNTHESIS OF FURAN-2-ACETIC ESTERS BY PALLADIUM-CATALYZED OXIDATIVE CYCLIZATION-ALKOXYCARBONYLATION OF (Z)-2-EN-4-YN-1-OLS

Authors
GABRIELE B SALERNO G DEPASCALI F SCIANO GT COSTA M CHIUSOLI GP
Citation
B. Gabriele et al., NOVEL SYNTHESIS OF FURAN-2-ACETIC ESTERS BY PALLADIUM-CATALYZED OXIDATIVE CYCLIZATION-ALKOXYCARBONYLATION OF (Z)-2-EN-4-YN-1-OLS, Tetrahedron letters, 38(39), 1997, pp. 6877-6880
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
39
Year of publication
1997
Pages
6877 - 6880
Database
ISI
SICI code
0040-4039(1997)38:39<6877:NSOFEB>2.0.ZU;2-H
Abstract
Furan-2-acetic esters are obtained in good yields by direct oxidative cyclization-alkoxycarbonylation of (Z)-2-en-1-yn-1-ols. bearing both a n alkyl or an aryl substituent alpha to the hydroxy group, in the pres ence of catalytic amounts of palladium iodide in conjunction with pota ssium iodide at 50-70 degrees C and 100 atm of a 9:1 mixture of carbon monoxide and air. (C) 1997 Elsevier Science Ltd.