A NEW METHOD FOR THE FORMATION OF THE IMIDAZO[4',5'3,4]PYRIDO[2,3-B]INDOLE RING - FORMAL SYNTHESIS OF THE ALKALOIDS FROM MARINE ORIGIN GROSSULARINE-1 AND GROSSULARINE-2

Authors
MOLINA P FRESNEDA PM SANZ MA
Citation
P. Molina et al., A NEW METHOD FOR THE FORMATION OF THE IMIDAZO[4',5'3,4]PYRIDO[2,3-B]INDOLE RING - FORMAL SYNTHESIS OF THE ALKALOIDS FROM MARINE ORIGIN GROSSULARINE-1 AND GROSSULARINE-2, Tetrahedron letters, 38(39), 1997, pp. 6909-6912
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
39
Year of publication
1997
Pages
6909 - 6912
Database
ISI
SICI code
0040-4039(1997)38:39<6909:ANMFTF>2.0.ZU;2-1
Abstract
A new synthesis of the thylamino-4-hydroxy-6-methoxymethyl-3H-imidazo[ 4', 5':3,4] pyrido[2,3-b]indole,used as key intermediate in the total synthesis of the alkaloids grossularines -1 and -2, based on the step- wise formation of the pyridine and imidazole rings, is described. (C) 1997 Elsevier Science Ltd.