A NOVEL, CHEMICALLY ROBUST, AMINE RELEASING LINKER

Authors
KAY C MURRAY PJ SANDOW L HOLMES AB
Citation
C. Kay et al., A NOVEL, CHEMICALLY ROBUST, AMINE RELEASING LINKER, Tetrahedron letters, 38(39), 1997, pp. 6941-6944
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
39
Year of publication
1997
Pages
6941 - 6944
Database
ISI
SICI code
0040-4039(1997)38:39<6941:ANCRAR>2.0.ZU;2-S
Abstract
A polymer supported sulfonamide 1, based on an amine protective group, has been developed as a novel linker for solid phase organic synthesi s. The linker permits the immobilisation of alcohol substrates, and re leases N-protected amines under mild nucleophilic cleavage conditions. (C) 1997 Elsevier Science Ltd.