SURVIVAL OF ESCHERICHIA-COLI-CELLS EXPOSED TO IODOACETATE AND CHLORODINITROBENZENE IS INDEPENDENT OF THE GLUTATHIONE-GATED K+ EFFLUX SYSTEMS KEFB AND KEFC

Authors
NESS LS FERGUSON GP NIKOLAEV Y BOOTH IR
Citation
Ls. Ness et al., SURVIVAL OF ESCHERICHIA-COLI-CELLS EXPOSED TO IODOACETATE AND CHLORODINITROBENZENE IS INDEPENDENT OF THE GLUTATHIONE-GATED K+ EFFLUX SYSTEMS KEFB AND KEFC, Applied and environmental microbiology, 63(10), 1997, pp. 4083-4086
Citations number
12
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Applied and environmental microbiology → ACNP
ISSN journal
00992240
Volume
63
Issue
10
Year of publication
1997
Pages
4083 - 4086
Database
ISI
SICI code
0099-2240(1997)63:10<4083:SOEETI>2.0.ZU;2-J
Abstract
The KefB and KefC systems of Escherichia coli cells are activated by i odoacetate (IOA) and chlorodinitrobenzene (CDNB), leading to a rapid d rop in the intracellular pH. However, survival of exposure to IOA or C DNB was found to be essentially independent of KefB and KefC activatio n. No correlation was found between the toxicity of the compound and i ts ability to elicit protective acidification via activation of KefB a nd KefC.