Objective, Previous researches pointed out the critical changes needed
to increase the efficiency of the National Screening Programme of Cer
vical Cancer in Mexico. These changes were assessed through a cost-ben
efit analysis. This paper presents the results of that appraisal. Figu
res are presented as USDollars of 1996 valued as 7.5 pesos for each do
llar Results. The operational unitary cost of the integral process of
the cytology - the obtention of the Pap smear, its transportation to t
he interpretation centre, its analysis,and the notification of results
to users-was estimated in US$ 11.6. lf the proposed changes are opera
ted, the cost of each citology would increase by 32.7%. The benefit/co
st ratio would be 2 and the net benefit of 88 millions of US dollars f
or the next five years. Conclusions. The operation of the proposed cha
nges is socially desirable, but should be supported the training activ
ities of the personnel, the increase of the coverage of women at risk,
the quality control activities, the monitoring of the program and the
communication with women detected as positive cases.