Hypercalcemia is the most common-metabolic disorder associated with ma
lignancies. Squamous cell carcinoma of the penis is a tumor for which
this abnormality has rarely been described. This report presents a cas
e of hypercalcemia seen in a patient with advanced penile cancer. A ch
emotherapy regimen of intravenous cisplatin and fluorouracil caused re
gression of the primary tumor and normalization of the serum calcium.
A literature review supported an association between squamous cell car
cinoma of the penis and hypercalcemia. (C) 1997 Wiley-Liss, Inc.