GAINING GREATER SELECTIVITY IN THE SUPERCRITICAL-FLUID EXTRACTION OF DIGOXIN FROM DIGITALIS-LANATA LEAVES

Authors
MOORE WN TAYLOR LT
Citation
Wn. Moore et Lt. Taylor, GAINING GREATER SELECTIVITY IN THE SUPERCRITICAL-FLUID EXTRACTION OF DIGOXIN FROM DIGITALIS-LANATA LEAVES, Phytochemical analysis, 8(5), 1997, pp. 238-243
Citations number
10
Categorie Soggetti
Biology,"Chemistry Analytical","Plant Sciences
Journal title
Phytochemical analysis → ACNP
ISSN journal
09580344
Volume
8
Issue
5
Year of publication
1997
Pages
238 - 243
Database
ISI
SICI code
0958-0344(1997)8:5<238:GGSITS>2.0.ZU;2-6
Abstract
As higher levels of modifier are employed in supercritical fluid extra ction, selectivity is diminished. This work discusses several strategi es for improving selectivity in the extraction of digoxin from Digital is lanata leaves. The three strategies for improving selectivity which were studied include the use of alternative fluids, inclusion of a pr e-extraction step, and selective rinsing of the solid phase trap. Adva ntages were realized with each technique, and it was concluded that th ey should be used in conjection with one another in order to maximize selectivity. (C) 1997 by John Wiley & Sons, Ltd.