Wh. Ahrens et Wr. Panaram, BASIS FOR THIFENSULFURON-INSECTICIDE SYNERGISM IN SOYBEANS (GLYCINE-MAX) AND CORN (ZEA-MAYS), Weed science, 45(5), 1997, pp. 648-653
Fresh weight reductions of greenhouse-grown soybeans and corn treated
with postemergence thifensulfuron at 4.4 g al ha(-1) were synergistica
lly enhanced when the herbicide was mixed with formulated chlorpyrifos
or malathion insecticides, bur the enhancement: was not observed with
formulated methomyl insecticide. Thifensulfuron plus formulants of ei
ther chlorpyrifos or malathion reduced fresh weights no more than did
the herbicide applied alone. Growth rare of hydroponically grown soybe
ans was reduced by root-applied thifensulfuron in combination with a f
oliar-applied formulation of chlorpyrifos or malathion, but not methom
yl. Postemergence-applied thifensulfuron reduced the growth rate of hy
droponically grown soybeans and corn with chlorpyrifos, malathion, or
methomyl applied postemergence 1 d before thifensulfuron and with proc
edures identical to those used for absorption, translocation, and meta
bolism experiments. None of the insecticides applied 1 d before thifen
sulfuron altered foliar absorption of C-14-thifensulfuron or its trans
location in unifoliolate soybeans or three-leaf corn. Thin-layer chrom
atography of soybean extracts revealed one primary thifensulfuron meta
bolite, presumably the deesterified free acid. C-14-thifensulfuron met
abolism in corn produced about five unidentified metabolites in apprec
iable amounts. Levels of unmetabolized C-14-thifensulfuron 24 h after
herbicide application were highest in insecticide-treated soybeans and
corn. Over all experiments, enhancement of injury and inhibition of t
hifensulfuron metabolism generally were greatest in soybeans with chlo
rpyrifos but were greatest in corn with chlorpyrifos or malathion. Syn
ergistic enhancement of thifensulfuron injury to soybeans and corn by
chlorpyrifos and malathion appears to result from insecticide inhibiti
on of thifensulfuron detoxication.