Ld. Girodier et Fp. Rouessac, A NEW SYNTHETIC ROUTE TO OPTICALLY-ACTIVE ALPHA-ALKYL-2-FURYLCARBINOLAND 3-FURYLCARBINOL BY INTRAMOLECULAR DIASTEREOSELECTIVITY, Tetrahedron : asymmetry, 5(7), 1994, pp. 1203-1206
We report the results of intramolecular asymmetric alkylation of enant
iomerically pure 2- and 3-furaldehydes containing a p-tolylsulfoxide g
roup, thus providing an efficient method of obtaining optically active
alpha-alkyl-2- and 3-furanmethanol of known configuration after cleav
age of the sulfoxide group. In example, R and S alpha-phenyl-3-furanme
thanol are described.