A NEW SYNTHETIC ROUTE TO OPTICALLY-ACTIVE ALPHA-ALKYL-2-FURYLCARBINOLAND 3-FURYLCARBINOL BY INTRAMOLECULAR DIASTEREOSELECTIVITY

Authors
GIRODIER LD ROUESSAC FP
Citation
Ld. Girodier et Fp. Rouessac, A NEW SYNTHETIC ROUTE TO OPTICALLY-ACTIVE ALPHA-ALKYL-2-FURYLCARBINOLAND 3-FURYLCARBINOL BY INTRAMOLECULAR DIASTEREOSELECTIVITY, Tetrahedron : asymmetry, 5(7), 1994, pp. 1203-1206
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
7
Year of publication
1994
Pages
1203 - 1206
Database
ISI
SICI code
0957-4166(1994)5:7<1203:ANSRTO>2.0.ZU;2-X
Abstract
We report the results of intramolecular asymmetric alkylation of enant iomerically pure 2- and 3-furaldehydes containing a p-tolylsulfoxide g roup, thus providing an efficient method of obtaining optically active alpha-alkyl-2- and 3-furanmethanol of known configuration after cleav age of the sulfoxide group. In example, R and S alpha-phenyl-3-furanme thanol are described.