ASYMMETRIC-SYNTHESIS .21. ENANTIOSELECTIVE REDUCTION OF KETONES CATALYZED BY NEW (4S,5R)-4,5-DIPHENYL-1,3,2-OXAZABOROLIDINE

Authors
JIANG YZ QIN Y MI AQ HUANG ZT
Citation
Yz. Jiang et al., ASYMMETRIC-SYNTHESIS .21. ENANTIOSELECTIVE REDUCTION OF KETONES CATALYZED BY NEW (4S,5R)-4,5-DIPHENYL-1,3,2-OXAZABOROLIDINE, Tetrahedron : asymmetry, 5(7), 1994, pp. 1211-1214
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
7
Year of publication
1994
Pages
1211 - 1214
Database
ISI
SICI code
0957-4166(1994)5:7<1211:A.EROK>2.0.ZU;2-O
Abstract
Oxazaborolidine prepared from (1R,2S)-1,2-diphenyl-2-aminoethanol with borane was used as catalyst in the enantioselective reduction of keto nes:Excellent enantioselectivities with e.e. > 99% For acetophenone an d e. e.> 96% for omega-bromo acetophenone have been achieved.