THE INFLUENCE OF EXTERNAL GAMMA-IRRADIATI ON ON THE STATE OF HORMONALLY ACTIVE TESTICULAR CELLS IN MALE-RATS

Authors
KONOPLYA EF AMVROSIEV AP POPOV EG CHANTURIA AV
Citation
Ef. Konoplya et al., THE INFLUENCE OF EXTERNAL GAMMA-IRRADIATI ON ON THE STATE OF HORMONALLY ACTIVE TESTICULAR CELLS IN MALE-RATS, Doklady Akademii nauk BSSR, 38(2), 1994, pp. 88-92
Citations number
15
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Doklady Akademii nauk BSSR → ACNP
ISSN journal
0002354X
Volume
38
Issue
2
Year of publication
1994
Pages
88 - 92
Database
ISI
SICI code
0002-354X(1994)38:2<88:TIOEGO>2.0.ZU;2-2
Abstract
The paper presents the original data on dose-dependent characteristics of Sertoli cell androgen reception in various periods after whole-bod y gamma-irradiation (10, 25, 50, 100 and 500X10(-2) Gy; at 6,2X10(-2) Gy/min), coupled with electron microscopy morphological characteristic s of these and other populations of testicular cells. The analysis of the data obtained suggests the existence of gamma-sensor in brain of m ammals, involved at hypothalamic-pituitary-testicular levels in realiz ation of stress radiation suppression of Sertoli cell function at very low (10-50X10(-2) Gy) doses by means of hypothalamic releasing factor s and pituitary gonadotropins hypersecretion.