This article summarizes the studies of the mechanism of electroacupunc
ture (EA) in the regulation of the abnormal function of hypothalamic-p
ituitary-ovarian axis (HPOA) in our laboratory. Clinical observation s
howed that EA with the effective acupoints could cure some anovulatory
patients in a highly effective rate and the experimental results sugg
ested that EA might regulate the dysfunction of HPOA in several ways,
which means EA could influence some gene expression of brain, thereby,
normalizing secretion of some hormones, such as GnRH, LH and E-2. The
effects of EA might possess a relative specificity on acupoints.