AN EBV-BASED VECTOR ALLOWING A HIGH-LEVEL OF LTR(HIV)-DIRECTED EXPRESSION IN HUMAN-CELLS

Authors
RAIMOND J PLESSIS C FARGETTE F LEGRAND A HEBERT E
Citation
J. Raimond et al., AN EBV-BASED VECTOR ALLOWING A HIGH-LEVEL OF LTR(HIV)-DIRECTED EXPRESSION IN HUMAN-CELLS, Plasmid, 32(1), 1994, pp. 70-74
Citations number
23
Categorie Soggetti
Genetics & Heredity
Journal title
Plasmid → ACNP
ISSN journal
0147619X
Volume
32
Issue
1
Year of publication
1994
Pages
70 - 74
Database
ISI
SICI code
0147-619X(1994)32:1<70:AEVAAH>2.0.ZU;2-9
Abstract
We have developed a vector that allows high and transactivable express ion of inserted genes. The vector contains a transcription unit in whi ch the LTR from HN flanks a multicloning site. The plasmid is based on the EBV p205 plasmid, which allows stable replication in human cells. The ability of the vector to express an exogenous DNA in human cells has been tested using the firefly luciferase gene. (C) 1994 Academic P ress. Inc.