Fb. Niessen et al., THE ROLE OF SUTURE MATERIAL IN HYPERTROPHIC SCAR FORMATION - MONOCRYLVS. VICRYL-RAPIDE, Annals of plastic surgery, 39(3), 1997, pp. 254-260
The development of hypertrophic scars and keloids is an unsolved probl
em in the process of wound healing, There are indications that inflamm
ation plays an important role in this process, but its exact mechanism
remains unclear. In this study the amount of inflammation and the dev
elopment of hypertrophic scars and keloids was investigated in inframa
mmary skin incisions sutured with synthetic absorbable suture material
s: a monofilamentous suture (Monocryl) compared with a multifilamentou
s suture (Vicryl-rapide). In 81 breast reduction patients Monocryl (N
= 28) has proved to give significantly smaller, less reactive scars wi
th a lower tendency toward hypertrophic scar formation compared with V
icryl-rapide (N = 53).