ATYPICAL LYME BORRELIOSIS IN AN HIV-INFECTED MAN

Citation
F. Cordoliani et al., ATYPICAL LYME BORRELIOSIS IN AN HIV-INFECTED MAN, British journal of dermatology, 137(3), 1997, pp. 437-439
Citations number
14
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
00070963
Volume
137
Issue
3
Year of publication
1997
Pages
437 - 439
Database
ISI
SICI code
0007-0963(1997)137:3<437:ALBIAH>2.0.ZU;2-T
Abstract
We report the fourth case of Lyme borreliosis in a man infected with h uman immunodeficiency virus (HIV), The erythema chronicum migrans was persistent, overlapping with meningoradiculitis. Repeated immunofluore scence tests for Borrelia burgdorferi sensu late remained negative in both sera and cerebrospinal fluid (CSP), the enzyme-linked immunosorbe nt assay was weakly positive in serum and CSF and a Western blot was p ositive. The skin infiltrate was composed mostly of T lymphocytes with a CD4/CD8 ratio of 0.5. The course of the disease was favourable afte r treatment with intravenous ceftriaxone, Further studies are necessar y to evaluate whether HIV infection influences, as does syphilis, the course and response to treatment of Lyme borreliosis. Serological test s are insufficiently sensitive and the Western blot assay is necessary to confirm Lyme disease in HIV-positive patients.