Jb. Jonas et Ae. Grundler, CORRELATION BETWEEN MEAN VISUAL-FIELD LOSS AND MORPHOMETRIC OPTIC DISK VARIABLES IN THE OPEN-ANGLE GLAUCOMAS, American journal of ophthalmology, 124(4), 1997, pp. 488-497
PURPOSE: To correlate morphologic changes of the optic disk with. mean
visual field defect in glaucoma, METHODS: Color optic disk photograph
s of 302 patients with primary open-angle glaucoma, 53 patients with p
seudoexfoliative glaucoma, and 55 patients with normal-pressure glauco
ma were morphometrically evaluated The data were correlated with mean
visual held defect, RESULTS: The correlation between mean visual field
defect: and neuroretinal rim area was similar to a logarithmic functi
on, The visual held deteriorated slightly in the early stage and marke
dly in the advanced stages of glaucoma, A discrepancy between normal v
isual field and abnormal optic disk occurred more often in young than
in old patients. Neuroretinal rim shape, total rim area, and rim area
in the temporal. inferior and temporal superior disk sectors correlate
d best. with mean visual field loss, Alpha and beta zones of peripapil
lary atrophy and diameter of retinal arterioles were less clearly corr
elated, Calculated rim variables that were corrected for optic disk ar
ea did not markedly improve the correlation coefficients Zn eyes with
normal visual fields, rim shape was the most important disk variable f
or detecting glaucomatous optic nerve damage, There were no patients w
ith glaucomatous visual field loss and an unremarkable optic disk, CON
CLUSIONS: In early glaucoma, changes are more marked in optic disk app
earance than in the visual field, suggesting that, at least for some p
atients, for early glaucoma diagnosis, optic disk appearance is more i
mportant than perimetry, whereas for follow-up examination, perimetry
may be more useful than optic disk morphometry, The most useful planim
etric optic disk parameters are neuroretinal rim shape and rim area.