PATHOGENETIC FEATURES OF HEMOPHILIA COURSE

Authors
KARGIN VD EGOROVA LV NAZAROVA NS KHARCHENKO MF EGOROVA VA ZUBAREVA TS LYSOVA LV BELYAEVA EV BUBNOVA LN
Citation
Vd. Kargin et al., PATHOGENETIC FEATURES OF HEMOPHILIA COURSE, Gematologia i transfuziologia, 42(3), 1997, pp. 29-32
Citations number
4
Categorie Soggetti
Hematology
Journal title
Gematologia i transfuziologia → ACNP
ISSN journal
02345730
Volume
42
Issue
3
Year of publication
1997
Pages
29 - 32
Database
ISI
SICI code
0234-5730(1997)42:3<29:PFOHC>2.0.ZU;2-P
Abstract
Pathogenetic features of hemophilia course. V. D. Kargin, L. V. Egorov a, N. S. Nazarova, M. F. Kharchenko, V. A. Egorova, T. S. Zubareva, L. V. Lysova, E. V. Belyaeva, L. N. Bubnova. Research Institute of Hemat ology and Transfusiology, St. Peterburg, Russia. 76 hemophiliacs were examined immunologically and biochemically for concentrations of glyco saminoglycans in leukocytes and platelets, plasma DNA, serum activity of poly-A-polymerase. 36 of them had severe disease with exacerbation of arthropathy. The authors have determined some biochemical and immun ological parameters the changes of which characterize severe and treat ment-resistant forms of hemophilia.