ANTILYMPHOCYTIC GLOBULIN - TREATMENT OF APLASTIC-ANEMIA

Authors
MIKHAILOVA EA SAVCHENKO VG MASLOVA ER USTINOVA EN
Citation
Ea. Mikhailova et al., ANTILYMPHOCYTIC GLOBULIN - TREATMENT OF APLASTIC-ANEMIA, Terapevticeskij arhiv, 69(7), 1997, pp. 33-39
Citations number
18
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
69
Issue
7
Year of publication
1997
Pages
33 - 39
Database
ISI
SICI code
0040-3660(1997)69:7<33:AG-TOA>2.0.ZU;2-A
Abstract
Made in Russia antilymphocytic globulin (ALG) was given to 43 patients with aplastic anemia (AA). 56% of the patients responded, 30% reached a complete or partial remission. 5-year actural sur vival of ALG-trea ted patients was 52% (44 and 60% for severe and non-severe forms). The data on ALG efficacy suggest its benefits in fist-line therapy of bot h severe and non-severe AA as well as in management of patients resist ant to other methods of immunosuppressive treatment.