As many as 1% of newborn infants have a prenatal diagnosis of hydronep
hrosis or significant renal pelvic dilation. Hydronephrosis often is c
aused by nonobstructive conditions. The likelihood of significant urol
ogic pathology is directly related to the size of the fetal renal pelv
is, and 90% with an anteroposterior diameter more than 2 cm need surge
ry or long-term urologic medical care. Following delivery, antibiotic
prophylaxis should be administered, and a renal sonogram and voiding c
ystourethrogram should be obtained. If there is grade 3 or 4 hydroneph
rosis, usually a diuretic renogram is recommended also. Pediatric urol
ogic or pediatric nephrologic consultation usually is helpful in plann
ing evaluation and treatment. Prenatal recognition of hydronephrosis a
llows neonatal diagnosis and treatment of urologic pathology, preventi
ng complications of pyelonephritis and obstruction.