SYNTHESIS AND ODOR OF CHIRAL PARTIAL STRUCTURES OF KHUSIMONE .2.

Authors
SPREITZER H PICHLER A HOLZER W SHAHABI M
Citation
H. Spreitzer et al., SYNTHESIS AND ODOR OF CHIRAL PARTIAL STRUCTURES OF KHUSIMONE .2., Helvetica Chimica Acta, 80(6), 1997, pp. 1857-1864
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Helvetica Chimica Acta → ACNP
ISSN journal
0018019X
Volume
80
Issue
6
Year of publication
1997
Pages
1857 - 1864
Database
ISI
SICI code
0018-019X(1997)80:6<1857:SAOOCP>2.0.ZU;2-2
Abstract
Khusimone (1), one of the main odor-donating compounds of vetiver oil, is subject of the following study on structure/odor relationship. Rin g opening of the carbonyl-functionalized bridge of the tricyclic khusi mone leads to the bicyclic structures 2a/b. The enantioselective appro ach to these degraded structures is described, and the olfactory conse quences are studied. Starting point of the synthesis is an enantiomeri cally pure enone ester which is easily obtainable from camphorsulfonic acid.