COLON-CANCER IN THE ELDERLY - EVIDENCE FOR MAJOR IMPROVEMENTS IN HEALTH-CARE AND SURVIVAL

Time trends in therapeutic approaches and in the prognosis of colon ca ncer for patients aged 75 years and above have been investigated in co mparison with corresponding trends for younger patients using a popula tion-based series of 2089 colon cancer patients diagnosed between 1976 and 1990 in the Cote-d'Or area (478 000 inhabitants), Burgundy, Franc e. Significant progress has been achieved in the management of patient s with colon cancer in both age groups, but trends have been more noti ceable in patients aged 75 years and above. In the elderly, the propor tion of cancers limited to the digestive tract wall showed a 3-year av erage increase of 2.8% (P=0.02) and the frequency of curative surgery an average increase of 8.6% (P<0.001), so that it was performed in 80% of cases in the last 3-year period. Operative mortality decreased by 2.5% between 3-year periods (P<0.004). Crude 5-year survival rates in elderly patients increased from 15% in the 1976-78 period to 29% in th e 1985-87 period (P<0.001), the corresponding figures being 36% and 44 % (P>0.10) in younger patients.